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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC9A1
All Species:
13.03
Human Site:
T774
Identified Species:
23.89
UniProt:
P19634
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19634
NP_003038.2
815
90763
T774
K
E
T
S
S
P
G
T
D
D
V
F
T
P
A
Chimpanzee
Pan troglodytes
XP_513239
793
88468
V758
R
L
Y
F
C
P
G
V
D
P
N
E
G
Q
E
Rhesus Macaque
Macaca mulatta
XP_001115213
427
46791
L398
E
T
L
I
F
I
F
L
G
V
S
T
V
A
G
Dog
Lupus familis
XP_535345
816
90951
T775
K
E
P
S
S
P
G
T
D
D
V
F
T
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61165
820
91449
T779
K
E
P
S
S
P
G
T
D
D
V
F
T
P
G
Rat
Rattus norvegicus
P26431
820
91629
T779
K
E
P
S
S
P
G
T
D
D
V
F
T
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514675
940
104115
E907
R
F
G
T
V
Q
E
E
G
L
A
E
G
T
R
Chicken
Gallus gallus
Q5ZJ75
574
64115
R545
Q
E
D
L
H
H
G
R
I
Q
M
K
T
L
T
Frog
Xenopus laevis
NP_001081553
781
87800
S747
I
P
Q
E
S
P
N
S
Q
R
L
Q
R
C
L
Zebra Danio
Brachydanio rerio
NP_001106952
653
73606
P624
P
A
N
R
P
E
S
P
R
R
A
R
L
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P35449
667
75263
E638
S
A
M
F
R
S
T
E
Q
L
P
S
E
T
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWU6
535
59320
N506
T
P
F
F
T
S
N
N
G
D
Y
D
D
E
G
Baker's Yeast
Sacchar. cerevisiae
Q04121
633
70130
V604
F
Q
N
F
D
E
Q
V
L
K
P
V
F
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.3
51.9
95.8
N.A.
92.4
93.2
N.A.
42.5
21.7
73.2
55.4
N.A.
N.A.
N.A.
33.1
N.A.
Protein Similarity:
100
86.9
52
97.5
N.A.
95
95.1
N.A.
57.7
39.7
81.8
68.9
N.A.
N.A.
N.A.
52.5
N.A.
P-Site Identity:
100
20
0
86.6
N.A.
86.6
86.6
N.A.
0
20
13.3
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
26.6
6.6
86.6
N.A.
86.6
86.6
N.A.
13.3
33.3
26.6
0
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.5
41.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
0
0
0
0
16
0
0
8
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
0
8
0
0
0
39
39
0
8
8
0
8
% D
% Glu:
8
39
0
8
0
16
8
16
0
0
0
16
8
8
8
% E
% Phe:
8
8
8
31
8
0
8
0
0
0
0
31
8
0
0
% F
% Gly:
0
0
8
0
0
0
47
0
24
0
0
0
16
0
39
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
8
0
0
8
0
0
0
0
0
0
% I
% Lys:
31
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% K
% Leu:
0
8
8
8
0
0
0
8
8
16
8
0
8
16
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
16
0
0
0
16
8
0
0
8
0
0
0
0
% N
% Pro:
8
16
24
0
8
47
0
8
0
8
16
0
0
31
8
% P
% Gln:
8
8
8
0
0
8
8
0
16
8
0
8
0
16
0
% Q
% Arg:
16
0
0
8
8
0
0
8
8
16
0
8
8
0
8
% R
% Ser:
8
0
0
31
39
16
8
8
0
0
8
8
0
0
0
% S
% Thr:
8
8
8
8
8
0
8
31
0
0
0
8
39
16
16
% T
% Val:
0
0
0
0
8
0
0
16
0
8
31
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _